Bioperine- Basically a pure and safe nutritional supplement of piperine, Bioperine can have several positive effects on our body. It contains about ninety five percent of piperine that is known to enhance the bioavailability of nutrients. As a result, bioperine intake helps in rapid absorption of nutrients from the gastrointestinal tract. Owing to its affinity for the fatty tissue, it even interacts with the lipid component of the intestinal cell membrane thereby allowing further nutrient permeability. It is quite popular due to its ability to enhance thermogenesis. This is how it works - the piperine present in bioperine stimulates the release of catecbolamines that trigger thermogenesis in the GI tract thus, making more energy available for digestion. It can be combined with other nutrients too to improve the health of human beings as well as animals.

Citric Acid ~

Cyclic Adenosine Monophosphate 3'-5'-cyclic adenosine monophosphate or Cyclic Adenosine Monophosphate, a second messenger that mediates the action of several eptide or amine hormones, is abbreviated as cyclic AMP or cAMP. cAMP is thus vital for varied biological processes and used for intracellular signal transduction in various organisms. This major communicator is a result of the action of the enzyme adenyl cyclase on ATP. As such, cyclic AMP performs many physiological functions and is also responsible for increasing blood glucose levels. Adrenaline that enhances blood sugar levels in the body is able to do so by stimulating cAMP production. Cyclic AMP plays an important role in the following: urine regulation synthesis of flagellar proteins in bacteria hormone release sensory and nerve processes Apart from these functions, it also helps in breakdown of lipids in some organisms to produce energy in the absence of sufficient glucose.

Dioscorea Villosa extract is a medicinal herb commonly knows as the wild yam. It has medicinal properties that help in curing the pain caused during menstrual cycle, stomach cramps, and discomfort from gallstones and rheumatoid arthritis. It has been used fro centuries by the Native Americans. It is also used by herbalists for female and childbirth related problems. Along with herbal medicine, this plant is of great use in the modern medicine as well. It is because of this plant that birth control pills are so commonly and easily available. Its steroid like property explains the vast usage of this plant for medicinal purposes. But consumption of this extract may also lead to a number of side effects. Vomiting, diarrhea, nausea and headache are some of the most common side effects of dioscorea villosa extract.

Evodiamine, an alkaloid extract from the Evodiae Fructus plant is known as Evodiamine. It has been referred to as a “hot nature” herb in Chinese literature and medicine. Based on animal studies, Evodiamine increases the natural fat burning rate and stimulates vanilloids for reduction of fat intake. It increases body temperature, influences the adrenal glands to secrete catecholamines and also affects the metabolism of certain drugs. Since it acts like a thermogenic and increases the overall temperature, more fat and calories are burnt due to its intake. This alkaloidal compound has anti obesity effects due to UCP1 (uncoupling protein 1) thermogenesis. In part, evodiamine can prevent diet induced obesity from developing further. It is available in the form of supplement or through Evodiae Fructus plant.

Glabra, commonly known as licorice, is a root used to extract a sweet flavor from. Licorice is a plant belonging to the legume family, like peas and beans. It takes two to three years after planting for licorice to be harvested in autumn. It requires deep, fertile, well drained soil with a lot of sun to be able to grow. The extract from licorice is produced by boiling the roots with water and then evaporating all the water. This extract is then sold both in the form of solid and liquid. Glabra consists of a sweetener called glycyrrhizin which is many times sweeter than sucrose. It is used in lot cough syrups and in ayurvedic medicine. Candies made from licorice roots are famous all over the world. Hence it is in many pharmaceutical and confectionery products.

Guggulsterone- Commiphora wightii, or the so called Guggul tree is a flowering shrub or rather a small tree which can grow up to a size of 4 meters. Once very common in India, it is now there listed as endangered, but not in northern Africa or elsewhere in central Asia. It was very popular in the Indian Ayurvedic medicine, but also currently in the western medicine for treating of heart problems. The hydrocarbon secretion of Guggul contains a plant sterol, guggulsterone, which in the human body seems to act as an antagonist to the farnesoid X receptor. Furthermore, guggulsterone is active in increasing the natural thyroid production. This in turn stimulates the metabolism and may raise the body temperature, burning stored excess fat.

L-Tyrosine, a non-essential amino acid that is used to build protein. It is a precursor dopamine, as well as a precursor to norepinephrine and epinephrine. The body makes L-Tyrosine from the amino acid phenylalanine. Since L-Tyrosine is a precursor of Dopamine, it may raise mental alertness, making it of great use in exercise programs.

Octopamine is related to noradrenaline. Octopamine was discovered by Vittorio Erspamer, an Italian scientist in 1948. Octopamine has a significant role in mollusks and is the central nervous system in snail. Octopamine also has a vital role in memory and learning in the fruit fly and honey bee. Octopamine is also useful for the firefly in releasing the light production. Octopamine mobilizes releasing fat in mammals and this has developed into promotion as a slimming aid on the internet. However, there is no apparent evidence about Octopamine facilitating weight loss. Octopamine also significantly increases the blood pressure in combination with stimulants such as weight loss supplements. This is extensively used in energy demanding insects such as spiders, lobsters, crabs and crayfish as their behaviors also include egg-laying, jumping and flying. Among vertebrates, Octopamine substitutes norepinephrine and as well exhibits common side effects. Octopamine is sited in the locust jump such that it modulates the muscle activity allowing the leg muscles to contract effectively.

Phosphatidylcholine has a role in membrane mediated cell signaling and is currently being experimented on weight loss treatments.

Phosphollipid complex is formed by the combination of lipids and phosphate. They are grouped into three categories. 1. Glycerophosphates- Glycerophosphates are one of the important factors for cell membranes. They are also responsible for intracellular messaging and act as a hormone stimulant. 2 Sphingophosphatides- These phospholipids are responsible for transportation of water and fat soluble materials through cell membranes. It also helps to stabilize water soluble compounds. 3. Glycolipids. They help to maintain the structure of the cell membrane by attaching themselves with other components. Phospholipids complex is important for maintaining physiological activity of the body as they are an important factor for bonding and formation of enzymes, amino acids, etc.

Quercetin is a flavanoid derived from plants and is widely used as a nutritional supplement. There are many studies which are being conducted to exactly determine the benefits of Quercetin. It is said to have antioxidant and anti-inflammatory properties and hence is being tested to help curb and cure terminal diseases like cancer. The high intake of fruits and vegetables is good for cancer treatments. Many researchers believe that these qualities of Quercetin are what allow it to be used for treating cancer as well. Quercetin is classified into the IARC group 3; which categorizes food and drugs as that which are not carcinogenic.

Rhodiola Rosea Extract can help increase resistance against fatigue and can reduce stress. Classified as adaptogens among the herbs, it prevents different harmful impacts caused by physical and mental stress and illness. Rhodiola Rosea is particularly helpful for athletes because of its adaptogenic properties and its capability to enhance efficiency of mitochondrial respiration in skeletal muscle. It also improves mental work capacity and resists mental fatigue. Research has found that it helps protect against cancer. It can also be beneficial for people who suffer from high altitude sickness. Its intake can better endurance exercise capacity in young people and may also benefit people suffering from certain kinds of glucose level and cardiac conditions. Rhodiola Rosea Extract helps prevent ischemic brain damage development.

Ribonucleic Acid - Derived from yeast, Ribonucleic Acid (RNA) is an antioxidant and plays a vital role in protein synthesis, and other chemical activities of cells. It passes genetic information from DNA to proteins made by the cells. It enhances the capability to learn. RNA also helps treat Alzheimer’s disease and depression, and increases energy levels. It tightens the skin, enhances sex drive and helps in countering aging effects. It is also helpful in recovery after surgical procedures and helps boost immune system response. It assists in improving prognosis of burn victims. A supplement containing RNA can reduce the incidence of peri-operative infections and improve healing of wound. It can also be helpful in epilepsy.

Smilax is actually a genus that contains over three hundred species, mainly found in sub-tropical and tropical areas throughout the world. These are climbing plants, many of which have flowers and bear some kind of fruit. Many smilax plants have found uses in medicine, some for symptom remedy of the premenstrual syndrome; some others for treatments of hormonal imbalance induced or aggravated skin diseases. Many smilax plants are being used in local cuisines, either for herbal drinks or for sweet snacks; moreover, a Chinese variant has a long history as treatment against syphilis. Smilax officinalis has found use with body building circles as sarsaparilla root, where the plant’s sterols seem to influence human’s metabolic processes. The belief of many herbalists is that S. officinalis is making the body produce more testosterone.

Taraxacum Officinale, more commonly called Dandelion, is a bitter diuretic from the Asteraceae family of plants. It performs as a stimulant to the system, concentrated on the urinary organs. When combined with other medicinal herbal agents, it is useful in the treatment of liver and kidney disorders, gallbladder and urinary disorders, jaundice, constipation, cirrhosis, dyspepsia, weaknesses of the heart, eczema and chronic joint and skin problems. Dandelion is also a mild laxative and can be taken in large amounts because it is not poisonous. It promotes good digestion and also increases the appetite.

Trimeylxanthine Anyhydrous is a form of caffeine that is found in many energy supplements. This stimulant is very beneficial for those who are looking to increase their energy and stamina levels. Trimelyxanthine anyhydrous is often combined with other ingredients to create various proprietary blends that are sold as weight loss supplements or energy supplements. Trimelyxanthine anyhydrous may also be marketed as a supplement that will bring about greater mental clarity, mental alertness, and focus. You can find this stimulant in both pill form and more potent powder form, although not generally sold alone but found as an active ingredient in other products.

Vinpocetine is a derivitate of the periwinkle plant and was developed in the latter part of the 1960’s. It can be used as a dietary supplement, which can be found online.

Vitamin B3, also called Niacin, is a water-soluble vitamin needed for the conversion of food into energy so that it may be used by the body. Vitamin B3 also helps metabolize protein, sugar and fat.