1-Androstene-3b-Ol,17-One is a compound rapidly becoming popular as a supplement for bodybuilders to increase testosterone levels. Before 1-Androstene-3b-Ol, 17-One came to shelves as a supplement 4-Androstenediol was the most popular supplement which gave great gains and libido increases, but it was banned worldwide by sports associations. 1-Androstene-3b-Ol, 17-One works similarly to 4-Androstenediol but it forms testosterone at a higher rate. The compound is converted to testosterone via the naturally occurring enzyme 3beta-HSD. It also does not convert to estrogen and/or DHT like older products. The use of 1-Androstene-3b-Ol, 17-One is legal and no association has yet objected to its use as a supplement.

Forskolin- the compound Forskolin comes from Coleus forskohlii, a plant that has been used in Hindu and Ayurvedic medicine for ages. Today, Forskolin is being extensively used in most advanced thermogenics and fat burners due its unique biological importance. Forskolin plays a vital role in weight loss owing to its natural fat-loss enhancing properties and also helps in maintaining healthy blood pressure levels, which are already in the normal range. It is a known fact that our body's metabolism depends on the hormones that are released by the thyroid and Forskolin boosts the production of these hormones. It also stimulates thyroid hormone release so as to increase the metabolic rate of the body further. Forskolin also offers various other health benefits due to its effect on cyclic adenosine monophosphate (cAMP), an important cell regulating compound.

Luteolin

Piperine, an extract that comes from the fruit of the black pepper plant “Piper Nigrum” and “Piper Longum,” sets the stage for the activities in the body that lead to digestion and intestinal absportion by increasing the metabolic process. It is a pungent substance that has been used in Ayurvedic medicine for treatment of various diseases and is commercially available. Piperine forms monochenic needles, is slightly soluble in water and even more so in alcohol, ether, or chloroform. It significantly enhances the body’s ability to absorb nutrients into the blood stream, and supports the body’s natural thermogenic activities. It inhibits human CYP3A4 and P-glycoprotein, which are enzymes that are important for transport of xenobiotics and metabolites. Piperin has been found to stimulate skin pigmentation when exposed to UVB light. Caution should be used by those on other medications if taking this extract because of piperin’s effects on drug metabolism.

Sodium Caprylate, in sub-fungistatic concentrations, shows interesting effects on fatty acid synthesis, metabolism, and pigmentogenesis of Trichophyton rubrum during its earlier growth phases. It significantly reduces fatty acid concentration. Carboxylic acids (sodium caprylate) have been utilized in preparing plasma products (precipitation of globulins) and inactivation of lipid-coated virus, but when therapeutic biologically active proteins are not present. Sodium caprylate has also been applied in association with heat and amino acids for virus inactivation. It can provide a proper caprylic acid concentration for virus inactivation. Because of dissociation reaction, non-iodized caprylic acid can be kept at an increased concentration at higher pHs by raising concentration of the ionized form (sodium caprylate) to kill viruses.