Menthol 1.25% is a solution of menthol. Menthol is extracted from peppermint oil or other mint oils. It is commonly used in some perfumery and tooth pastes. Menthol is also used in creams for pain and joint relief because research shows that menthol stimulates cold receptors on skin which causes the feeling of coldness and an analgesic effect. It is also shown to dilate blood vessels. Research shows that menthol provides temporary relief from minor aches and pains of muscles and joints, which are due to simple backaches. It also provides relief to patients with arthritis, strains, bruises, and sprains. Menthol depresses the sensation of pain by stimulating a thermal effect.