Caffeine, a central nervous system stimulant used in Designer Supplements Adrenalean as an aid to stay awake, for mental alertness due to fatigue or, in combination with other ingredients for pain relief, and as a power and energy accelerate. Caffeine is available alone as a non-prescription drug over the counter medication, in combination with other non-prescription drugs, and in prescription drug combinations for relief of pain and headache. Like Ephedra, caffeine acts to increase mental alertness while providing additional energy for weight loss and exercise training. Caffeine is more than a stimulant as it goes deep into muscles to provide long lasting power while delaying the onset of muscle fatigue. Also great before working out, caffeine fights fatigue and helps you get ready for your workout. For dieters feeling sluggish that need just a little something extra to get them through the day, caffeine is the obvious no-calorie stimulant solution. Many products containing caffeine anhydrous contain as much caffeine as one or two cups of coffee. It is recommended to limit the use of caffeine containing medications, foods, or beverages while taking caffeine supplements as excess caffeine intake may cause nervousness, irritability, sleeplessness and occasional rapid heart beat.

Evodiamine has been used in Chinese medicine and by Chinese herbalists for centuries for weight loss purposes. It is an extract from a plant, Evodia or Tetradium, actually a tree genus of the family Rutaceae. The bee bee tree, as it is called besides Euodia and Evodia, provide a bioactive alkaloid that the Chinese have nicknamed Wu-Chu-Yu. This extract not only can interact with UCP1, a thermogenic protein, which as a consequence burns energy as heat, but also has shown in studies on mice to reduce the fat uptake. Evodiamine seems to increase the resting temperature of humans, whereby increased fat and calories are burned in order to supply the heat. Deemed a breakthrough in thermogenesis, evodiamine is subject of several clinical studies.

Hordenine, which is also known as N-Dimethyl-hydroxyphenylethylamine, is a phenylethylamine alkaloid, which naturally occurs in barley seeds, but also in several cactus plants. The phenomenal antibiotic and antibacterial properties have long been recognized by the medical community, where in particular penicillin resistant Staphylococcus bacteria can be successfully restrained. Hordenine stimulates norepinephrine release and is therefore deemed a direct central nervous system stimulant. Norepinephrine, in turn, is a hormone that works as a lipolytic, aiding in liberating the stored fat from the cells and make it available for burning during the workout. The body building community commonly uses Hordenine as a weight loss agent. Furthermore, it seems that Hordenine is slowing down the digestive process, thereby slowing down the calorie transfer, allowing the excess fat to be burned, while retaining the feeling of satiation.

L-Huperzine A is extracted from a Chinese herb called Huperzia Serrata. L-Huperzine A inhibits the breakdown of Acetylcholinesterase that aids in raising the level of Acetylcholine, a memory neurotransmitter. It also helps in strengthening the brain’s NMDA receptors (N-methyl D-aspartate) that enhances the communication between the brain cells resulting to enhanced concentration, focus, learning and other brain functions. L-Huperzine A also stimulates the synthesis of nerve growth factor that is responsible for maintaining and promoting youthful and healthy brain function. L-Huperzine A quickly and potently boosts the memory, learning and the concentration functions of the brain for a short period of time.

Methylaricaiden

Phenylethlamine HCL is a salt of phenylethylamine. It is a crystalline solid and is formed by treating phenylethylamine with HCl. Its IUPAC name is 2 phenylethylamine HCl. The scientific name elucidates its chemical structure. It is an aromatic compound meaning that it has a basic benzene ring. It further has a two carbon chain attached at position 2 of the ring and the chain terminates in an amino group. It occurs naturally in some foods like chocolates but the food item might get metabolized too quickly sometimes for it to have a significant effect on the body. This substance has quite profound effects on the level of dopamine in the central nervous system, provided it passes the blood brain barrier. It increases dopamine level and at the same time inhibits dopamine transmitters resulting in a buildup of dopamine in the brain. While excessive levels of dopamine in the CNS are not healthy, the neurotransmitter does regulate cognition, mood, voluntary movement and other brain functions.

Quercetin, a bioflavonoid derived mostly from blue-green algae. Quercetin is a strong antioxidant commonly found in onions, wine and tea.

Synephrine HCL- Designed primarily to encourage fat loss. This is achieved by stimulating the beta-3 receptors. Doing so increases the metabolic rate leading to fat loss. Synephrine is a stimulant similar to caffeine and ephedrine and it is believed to provide an energy boost, suppress appetite and increase metabolism. The combination of all leads to burning more calories. Studies have stated that synephrine stimulates fat metabolism without the usual negative cardiovascular side effects. The effectiveness of synephrine is increased by combining it with HCL. This allows for increased absorption and more solubility in water. However regardless of the increasing popularity of synephrine HCL, there are still some debates over its over all effects and it being used as an alternative to ephedrine, a substance made illegal by many countries due to the side effects including heart disease.