Caffeine is a methylated xenthine discovered in 1819 by Friedrich Ferdinand Runge, a German chemist. Sources of Caffeine include beans, fruit and leaves of some plants. Caffeine available for human consumption is most commonly extracted from the coffee plant cherries and tea bush leaves, as well as foods and drinks that contain products derived from the kola nut. Caffeine can temporarily reduce the sensation of being tired; however, this does not mean that it eliminates the need for sleep. Generally, twenty five to fifty milligrams of caffeine is enough for most consumers to report an increase in alertness and arousal. Caffeine should be not be consumed by those with fecal incontinence as it relaxes the internal anal sphincter muscles.

Evodiamine- Tetradii Fructus, the fruit of the evodia plant, also known as Tetradium rutaecarpa, contains an active element that has recently been identified as evodiamine. This chemical compound is believed to be somewhat similar to capsaicin, the active compound found in the chili peppers. Some studies suggested that this vanilloid receptor agonist may interact with thermogenin, otherwise known as the uncoupling protein 1, UCP1, which is able to generate heat by a mechanism called thermogenesis. Tetradium rutaecarpa has been traditionally used in Chinese medicine for weight loss purposes and current studies seem to verify this information. Evodiamine has been embraced as a dietary supplement directed at weight loss, predominantly by the body building circles. This supplement is deemed to have energy burning and fat reducing, as well as diuretic properties.

Hordenine has antibacterial and antibiotic properties and is another weight loss agent that also stimulates the central nervous system.

L-Huperzine A is extracted from a Chinese herb called Huperzia Serrata. L-Huperzine A inhibits the breakdown of Acetylcholinesterase that aids in raising the level of Acetylcholine, a memory neurotransmitter. It also helps in strengthening the brain’s NMDA receptors (N-methyl D-aspartate) that enhances the communication between the brain cells resulting to enhanced concentration, focus, learning and other brain functions. L-Huperzine A also stimulates the synthesis of nerve growth factor that is responsible for maintaining and promoting youthful and healthy brain function. L-Huperzine A quickly and potently boosts the memory, learning and the concentration functions of the brain for a short period of time.

Methylaricaiden

Phenylethlamine HCL is a salt of phenylethylamine. It is a crystalline solid and is formed by treating phenylethylamine with HCl. Its IUPAC name is 2 phenylethylamine HCl. The scientific name elucidates its chemical structure. It is an aromatic compound meaning that it has a basic benzene ring. It further has a two carbon chain attached at position 2 of the ring and the chain terminates in an amino group. It occurs naturally in some foods like chocolates but the food item might get metabolized too quickly sometimes for it to have a significant effect on the body. This substance has quite profound effects on the level of dopamine in the central nervous system, provided it passes the blood brain barrier. It increases dopamine level and at the same time inhibits dopamine transmitters resulting in a buildup of dopamine in the brain. While excessive levels of dopamine in the CNS are not healthy, the neurotransmitter does regulate cognition, mood, voluntary movement and other brain functions.

Quercetin is a flavanoid derived from plants and is widely used as a nutritional supplement. There are many studies which are being conducted to exactly determine the benefits of Quercetin. It is said to have antioxidant and anti-inflammatory properties and hence is being tested to help curb and cure terminal diseases like cancer. The high intake of fruits and vegetables is good for cancer treatments. Many researchers believe that these qualities of Quercetin are what allow it to be used for treating cancer as well. Quercetin is classified into the IARC group 3; which categorizes food and drugs as that which are not carcinogenic.

Synephrine HCL- Designed primarily to encourage fat loss. This is achieved by stimulating the beta-3 receptors. Doing so increases the metabolic rate leading to fat loss. Synephrine is a stimulant similar to caffeine and ephedrine and it is believed to provide an energy boost, suppress appetite and increase metabolism. The combination of all leads to burning more calories. Studies have stated that synephrine stimulates fat metabolism without the usual negative cardiovascular side effects. The effectiveness of synephrine is increased by combining it with HCL. This allows for increased absorption and more solubility in water. However regardless of the increasing popularity of synephrine HCL, there are still some debates over its over all effects and it being used as an alternative to ephedrine, a substance made illegal by many countries due to the side effects including heart disease.