Biotin is required for the fatty acids and glucose formation so that essential energy is produced. Biotin also assists in the metabolism of fats, proteins and carbohydrates. Biotin is available in food naturally and the dietary sources of biotin comprise of brewer’s yeast, cauliflower, bananas, egg yolks, salmon, liver, sardines, mushrooms and legumes. The deficiency of biotin is uncommon. The other possibilities for having biotin as deficiency is genetic biotin deficiency, surgical stomach removal, excessive consumption of alcohol and infant dermatitis. Biotin deficiency leads to hair loss, skin rash, heart problems and high cholesterol. Biotin supplements are effective for eczema, acne, diaper rash, brittle nails and hair loss. People having a history of seizures should avoid using biotin. This is a B vitamin that helps in converting food to energy. It is mandatory that minimum 30 mg is taken daily as there are adequate health benefits. Normal biotin intake strengthens fingernails and also controls blood sugar levels.

Caffeine is extracted from coffee and tea during the process of decaffeination. Caffeine Anhydrous can be produced from dimethyl urea and malonic acid. It stimulates the central nervous system, enhancing the focus, concentration, and alertness, and warding off drowsiness. It is a mild diuretic and can also increase the metabolism. It increases the energy level and reduces fatigue. Aside from increasing mental alertness, it also helps in maximizing weight loss training. It stimulates the metabolism that helps the body to burn fat faster and uses the fat as energy. It also provides physical energy and delays the onset of fatigue.

Chromium Picolinate is a combination of chromium and picolinate acid. Combined with exercise, it is commonly used to lose weight through reducing appetite, increasing metabolism rate and melting fats. This, however, has not been proved clinically. It is also believed to increase energy, life span, prevent acne and improve a person’s mood. Being considered a natural alternative to steroids, it is recommended to athletes. Chromium is found in fish, poultry, whole-grains, cheese and meat. It helps in the proper working of cells by improving the efficiency of insulin. Picolinate acid helps in the proper absorption of chromium. A combination of chromium picolinate and other supplements may be risky, hence professional advice should be sought before using it. Pregnant or nursing women should also be careful.

Hoodia Gordonii, which although popular, has no published randomized controlled trials in humans to show hoodia is safe or effective in pill form. One study published in the September 2004 issue of Brain Research found that injections of p57 (The Active ingredient in Raw, Fresh Cut Hoodia, not dried) into the appetite center of rat brains resulted in altered levels of ATP, an energy molecule that may affect hunger. The animals receiving the P57 injections also ate less than rats that received placebo injections. However, this was an animal study and INJECTIONS IN THE BRAIN are very different from oral consumption, so it cannot be used to show that oral hoodia can suppress appetite in humans. Hoodia Gordonii is a succulent (a cactus of the aloe family) found in the Kalahari desert of South Africa. Most Hoodia Gordonii products contain very little, if any of the active ingredient needed to suppress hunger. Real Hoodia is very rare and is even an endangered plant. Most importantly, Hoodia has only demonstrated any effect in fresh, raw pieces of the plant. The effectiveness of powdered Hoodia has yet to be shown and may actually increase hunger. It's main use is as a cheap alternative to the more expensive weight loss herbs, which are the only alternative left after the banning of ephedra. Most supplement manufacturers can not use the more expensive weight loss herbs because it will result in a product that would be too expensive to compete with other more popular inexpensive diet supplements.

Niacin, also called Vitamin B3, exists in two main forms, niacin and niacinamide. The niacin form produces a flushing and itching of the skin when taken at higher dosages and this feeling is only temporary.

Pantothenic Acid is thought to reduce lactic acid accumulation in athletes, may improve oxygen utilization efficiency, and is believed to improve the body's ability to heal and possibly help in reducing acne

Vitamin B1, or rather the Vitamin B complex, is a group of vitamins that are all soluble in water and very often coexist in food sources. While every single Vitamin from the B complex group has a name, they are very often referred to by the number added to the Vitamin B group name, like Vitamin B1, which is thiamine, or Vitamin B2, which is riboflavin. Some other compounds have been added to the Vitamin B group at some time, but were later dropped, like adenine, orotic acid or adenosine monophosphate, where later research found that they are either synthesized by the human body or simply no Vitamins. Vitamin B complex supports the metabolism rate, maintains muscle tone and skin, raises functions of the nervous system and the immune system, promotes red blood cells and cell growth and division and much more.

Vitamin B2 , also called Riboflavin, is naturally manufactured by the body. Vitamin B2 is needed for the proper use of oxygen and amino acids, carbohydrates and fatty acids. Vitamin B2 is also utilized by Vitamin B6 in the body and is used to manufacture niacin. Vitamin B2 is especially needed when eating large amounts of protein.

Vitamin B6- There are three traditionally considered forms of vitamin B6: pyridoxal (PL), pyridoxine (PN), pyridoxamine (PM). The phosphate ester (PLP) has a leading role in metabolism of human body. It is obtained from the diet since humans cannot manufacture it. PLP is crucial in over 100 enzymes that enable important chemical reactions in the human body. In the brain, the manufacture of neurotransmitters like serotonin from tryptophan is made possible by PLP. PLP is also a coenzyme in the production of the iron coating component of hemoglobin called heme. Signs of vitamin B6 deficiency include irritability, depression and confusion, inflammation of the tongue, sores or ulcers of the mouth and the skin at the corner of the mouth.