Caffeine is a methylated xenthine discovered in 1819 by Friedrich Ferdinand Runge, a German chemist. Sources of Caffeine include beans, fruit and leaves of some plants. Caffeine available for human consumption is most commonly extracted from the coffee plant cherries and tea bush leaves, as well as foods and drinks that contain products derived from the kola nut. Caffeine can temporarily reduce the sensation of being tired; however, this does not mean that it eliminates the need for sleep. Generally, twenty five to fifty milligrams of caffeine is enough for most consumers to report an increase in alertness and arousal. Caffeine should be not be consumed by those with fecal incontinence as it relaxes the internal anal sphincter muscles.

Camellia Sisensis .

Capsaicin is used in several skin preparations and is used to relieve pain. It is available in the market in various forms such as ointments, creams, gels, liquids, lotions, sticks and pads under marketing names such as Capsagel, Zostrix, Arthricare for Women and Icy Hot Arthritis Treatment. A very astonishing fact is that capsaicin happens to be the active part of chili peppers. Though it is an irritant producing burning sensation on any tissue that comes in contact with it, it depletes substance P. Substance P transmits impulses of pan to the brain. It relieves pain due to diseases such as osteoarthritis, diabetes neuropathy and rheumatic arthritis. Capsaicin has not had any drug interactions till date. But this does not means that it can never have any interaction with any other drug. It is always best to confirm with your doctor if you really need to use capsaicin. Also, it is best to use this drug only in specified quantities.

Polyphenols.

Yohimbe is an evergreen tree which grows in Africa. Traditionally yohimbe is used as an aphrodisiac but it also acts as a powerful antioxidant. It’s usually taken in the form of tea or capsules or tablets. It is also used for impotence, depression, sexual problems in both men and women, in high blood pressure, low blood pressure and for chest pains. Yohimbe bark is also used to treat fever, cough and leprosy. It is also used as an anesthetic to dilate pupil, to prevent heart disease and as a hallucinogen. Yohimbe also helps in weight loss as it contains nor-epinephrine which increases metabolism. Yohimbine an active ingredient taken from bark of yohimbe is used in drugs to treat various disorders.